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FDA Approves Lilly’s Obesity Drug Zepbound

Tirzepatide injection becomes the first obesity drug that activates both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1.

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By: Kristin Brooks

Managing Editor, Contract Pharma

Eli Lilly and Co.’s Zepbound (tirzepatide) injection, the first obesity treatment that activates both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) hormone receptors. Zepbound is indicated for adults with obesity or those who are overweight and also have weight-related medical problems such as hypertension, dyslipidemia, type 2 diabetes mellitus, obstructive sleep apnea or cardiovascular disease.    The approval was based on results from the phase...

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